What Is Hyaluronidase?

Hyaluronidase is an enzyme that breaks down hyaluronic acid (HA). When injected into an area with HA filler, it rapidly dissolves the product — typically within 24-48 hours. It's the "undo button" for filler complications.

⏱ Speed

Results visible within 24-48 hours. Most filler dissolved within the first session.

Safety

Hyaluronidase is a medicine. In Sweden only doctors, or people with a special authorisation, may prescribe medicines; nurses with such authorisation may only prescribe medicines listed by the Swedish Medical Products Agency (IVO report 2024, in Swedish). Allergic reactions are rare but possible. A planned treatment may start with a skin test; a suspected blocked blood vessel is an emergency and treatment must not be delayed.

Sessions

1-3 sessions depending on filler volume and product type. Some products require more enzyme.

When To Consider Dissolution

  • Filler migration — product has moved from the intended area
  • Asymmetry — uneven results that can't be corrected with more filler
  • Overcorrection — too much volume was injected
  • Vascular compromise — emergency: filler compressing blood vessels (immediate treatment required)
  • Personal preference — you simply want to return to your natural appearance

The Procedure

  1. Consultation: Your provider assesses the area and determines how much hyaluronidase is needed.
  2. Allergy test (planned treatments): A small amount may be injected into the forearm first.
  3. Injection: Hyaluronidase is injected directly into the filler. You may feel a slight stinging sensation.
  4. Massage: The area is gently massaged to distribute the enzyme evenly.
  5. Wait: Results develop over 24-48 hours. A follow-up appointment is scheduled.

What To Expect After

Swelling is normal for 1-3 days. The dissolved area may initially look "over-corrected" (too flat). This normalizes within a week. You can re-inject new filler after 2-4 weeks once the hyaluronidase has fully cleared.

Preparing for dissolution?

Proper aftercare significantly improves your recovery and results.

Aftercare Guide →